Labeled as the next best thing to Botox, Argireline is a non-toxic muscle relaxing ingredient that helps to smooth out wrinkles when used topically.

Although Argireline has been around for many years, it didn’t really capture the attention of most beauty care manufacturers until Dr. Oz promoted it as one of the best ingredients to be found in eye creams.

Today, skin care companies use this ingredient often in combination with other anti-aging ingredients to help reduce the signs of aging. So, if you are looking for the best face cream with argireline, then one of the products in this review may be what you need.

Perfect Image Hydrating Repair Peptide Wrinkle Cream

While this Perfect Image Wrinkle Cream is specifically designed to treat dry reddened skin after a “criminal peel’, many people it once or twice a day to help moisturize their skin and reduce wrinkles.

Features of this face cream include:

  • Contains Matrixyl 3000 and Argireline to relax muscle tension and encourage the production of collagen.
  • Good for wrinkles, fine lines, rough, dry, dehydrated skin, stretch marks and cellulite.
  • Professionally formulated hydrating repair kit.
  • 1.7 ounces.


Distilled Water, Aloe Vera Gel, Cetyl Alcohol, Glycerin, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Hyaluronic Acid, Stearic Acid, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Sorbitan Stearate, Propylene Glycol, Diazolidinyl Urea, Iodopropynyl Butylcarbamate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Triethanolamine, Green Tea Leaf Extract, Cucumber Fruit Extract, Chamomile Extract, Comfrey Leaf Extract, Retinol Palmitate.


Place a small amount of this face cream on your fingertips and gently massage into the affected area using upward and outward strokes. Massage into your skin for 15 to 20 seconds.


The reviews are exceptionally good with the majority of users finding this Argireline face cream effective at treating dry and wrinkled skin. Few users experienced a burning sensation, but overall users found this cream safe and effective.

Here are some of the benefits they found using it:

  • Absorbs Easily– People liked that fact that it absorbs quickly, leaving behind no greasy residue.
  • Improves Skin’s Texture– They also find that this cream soothes their skin almost immediately and overtime they see that their skin begins to heal. Most users feel that their complexion feels softer and more pliable.
  • Reduces Wrinkles– Perfect Image Hydrating Repair Peptide Wrinkle Cream reduces fine lines and wrinkles.

There is no report of this skin cream either reducing stretch marks or cellulite.

Face Whisperer Day Cream With Argireline

The Face Whisperer Day Cream with Argireline is designed for people with normal or dry skin to help moisturize while also reducing the signs of aging. Let’s have a look at some of its features:

  • Reduces up to about 30% of those fine lines and wrinkles in about a month.
  • Moisturizes and nourishes skin with vitamins and minerals.
  • Contains both Argireline to relax muscle tension and Trylagen to boost collagen production.
  • 50 ml jar.


Water, Cetyl Alcohol, Sodium Acrylate/Sodium Acryloyl Dimethyl Taurate Copolymer, Glyceryl Stearate, Caprylic/Capric Triglyceride, Glycerin, Sweet Almond Oil, Acetyl Hexapeptide-8, Cetyl Alcohol, Sodium Polyacrylate, Dimethicone, Saccharide Isomerate, Trylagen®: Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1, lecithin, Xanthan Gum, Carbomer, triethanolamine, Phenoxyetanol, Butylene Glycol, Caprylyl Glycol; Ubiqinone 50, Squalane, Sodium Carboxymethyl Betaglucan, Aloe Vera Gel, Propylene Glycol, Diazolidinyl Urea, Iodopropynyl Butylcarbamate, Sodium EDTA, Avocado Fruit Extract, Carrot Root Extract, Cucumber Fruit extract, Ginseng Root Extract, Linden Tree Leaf Extract, Tromethamine.

How to Use

Dot face cream on face focusing on the forehead, under eye area, and wherever there are fine lines and wrinkles. Gently smooth in.


Reviews for Face Whisperer Day Cream are good with the majority of users finding that this face cream does what it intends to do. There are a few users who experienced breakouts after using this product but these complaints are the exception rather than the rule.

Benefits users experience when using this day cream are:

  • Goes on Smoothly– People state that this cream goes on smoothly and absorbs quickly, making the skin feel more moisturized almost instantly. With continued use they find that their skin feels smoother and looks healthier.
  • Reduces Wrinkles– Most users see a reduction in wrinkles in just few weeks time, and state that with regular user their skin looks noticeably younger.

ETal Anti Wrinkle Moisturizer Cream

Etal Anti Wrinkle Moisturizing Cream not only contains Argireline and Matrixyl 3000 but also a number of vitamins and minerals.

Features of this cream include:

  • Contains known anti-aging ingredients such as Hyaluronic acid, Matrixyl 3000, Argireline and Renovage as well as vitamins A, B3, and E.
  • Stimulates collagen production and reduces fine lines and wrinkles.
  • Firms skin.
  • Paraben free.


Aqua, cetearyl olivate, sorbitan olivate, cetearyl alcohol, coco-caprylate, Argireline®, Renovage®, Matrixyl®3000, niacinamide, sodium hyaluronate, xylitol, Vitamin C, glycerin, Vitamin E, Vitamin A, shea butter, aloe vera leaf juice, green tea leaf extract, boron nitride, sclerotium gum, orange fruit extract, phenoxyethanol, caprylyl glycol, potassium sorbate.

How to Use

Smooth into clean face on face and neck twice a day (morning and night.)


Etal Anti Wrinkle Moisturizing Cream receives almost perfect reviews. Benefits of this moisturizer are:

  • Absorbs Well– This face cream absorbs well, leaving the skin feeling healthy and smooth while helping to hydrate it, too.
  • Non-Irritating– Users are pleased that this product does not irritate or cause acne breakouts.
  • Plumper and Tighter Skin– People actually feel that after using this facial cream, their skin looks plumber, firmer and has fewer wrinkles.

In conclusion, if you are looking to reduce those fine lines and wrinkles, finding a good moisturizing cream that contains argireline may actually help you look and feel younger.